GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs7714584 | 1 | rs11167515 | chr5:150239471 | LOC134466 | chr5:150310000-150326146:- | 0.5 | 6.3 | 8.38E-10 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs11167518 | chr5:150258920 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.22 | 1.33E-9 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs11167519 | chr5:150265407 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.24 | 1.17E-9 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs11167520 | chr5:150265639 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.24 | 1.17E-9 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs11167521 | chr5:150271785 | LOC134466 | chr5:150310000-150326146:- | 0.45 | 5.81 | 1.33E-8 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs11167526 | chr5:150332481 | LOC134466 | chr5:150310000-150326146:- | 0.65 | 7 | 1.15E-11 | Crohn's disease |
| BLCA | cis | rs12220238 | 1 | rs111704178 | chr10:75957251 | ADK | chr10:75910965-76469059:+ | 0.3 | 4.62 | 5.23E-6 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs703842 | 1 | rs11172333 | chr12:58170335 | FAM119B | chr12:58166383-58176323:+ | 0.28 | 4.39 | 1.48E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172333 | chr12:58170335 | TSFM | chr12:58176536-58191367:+ | -0.4 | -7.05 | 8.18E-12 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172333 | chr12:58170335 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.25 | -4.26 | 2.6E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172335 | chr12:58175201 | FAM119B | chr12:58166383-58176323:+ | 0.28 | 4.29 | 2.3E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172335 | chr12:58175201 | TSFM | chr12:58176536-58191367:+ | -0.39 | -6.81 | 3.7E-11 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172335 | chr12:58175201 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.23 | -3.98 | 8.12E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172342 | chr12:58187758 | FAM119B | chr12:58166383-58176323:+ | 0.28 | 4.37 | 1.6E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs11172342 | chr12:58187758 | TSFM | chr12:58176536-58191367:+ | -0.38 | -6.72 | 6.57E-11 | Multiple sclerosis |